Remove this presentation flag as inappropriate i dont like this i like this remember as a favorite. Rhabdovirus, lyssavirus genus the family rhabdoviridae consists of more than 185 different viruses isolated from both plants and animals. Plant rhabdoviruses are transmitted by aphid, leafhopper or planthopper vectors, and the viruses replicate in both their insect and plant hosts. Pdf structure, interactions with host cell and functions of. Full text full text is available as a scanned copy of the original print version. After inoculation, rabies virus may enter the peripheral nervous system directly and migrates to the brain or may replicate in muscle tissue, remaining sequestered at or near the entry site during incubation, prior to central nervous system invasion and replication. Rhabdoviridae definition of rhabdoviridae by medical dictionary. Links to pubmed are also available for selected references. They first transcribe a positive rna template, then use that template to regenerate their negative rna genome. Moreover, members of the genus have been observed in andor isolated from vertebrate, invertebrate and plant tissues, since the first report of the international committee on nomenclature of viruses icnv in 1971, in. Rabies virus, epidemiology, transmission and freeroaming. Rabies ppt free download as powerpoint presentation.
A read is counted each time someone views a publication summary such as the title, abstract, and list of authors, clicks on a figure, or views or downloads the fulltext. There has never been a reported case of rabies infec tion via a blood transfusion. Rhabdoviridae is a family of viruses whose members infect vertebrates, invertebrates, and plants see jackson et al. Rhabdovirus single stranded,linear,negative sense,non segmented rna these are enveloped bullet shaped virus multiply in cytoplasm 2. Food and drug administration fda science board subcommittee. The family rhabdoviridae is ecologically diverse and includes viruses that infect a.
Rhabdoviridae proteins involved in replication and transcription. Choose from 60 different sets of rhabdovirus flashcards on quizlet. All plant rhabdoviruses carry analogs of the five core genes. Most virologists and microbiologists have heard of rabies virus, but few will fully appreciate the full scope of the viruses classified into the six genera of the rhabdoviridae family. Virus is associated with the buffy coat fraction of the blood. Complete study demonstrating the absence of rhabdovirus in a. Here we show that rhabdoviruses, a family of rna viruses that infect hosts as diverse as plants, insects and. In the present study, we engineered an attenuated maraba strain, defined as mg1, to.
Identification of a novel rhabdovirus in spodoptera. Importantly there is no definitive clinical presentation for rabies and in all. The vesicular stomatitis virus is a member of the rhabdovirus family. Rabies widely spread in asia and africa rabies is widely distributed across the globe. The rhabdoviridae family is comprised of over 150 viruses of vertebrates, invertebrates and plants. Viremia has not been demonstrated, and the virus is intraneuronal during the incubation period.
Full text get a printable copy pdf file of the complete article 444k, or click on a page image below to browse page by page. Rhabdoviridae international committee on taxonomy of. It affects humans as well as domestic and wild animals. The virus ability to gain access to aquaculture farms has also positioned it as a disease of utmost priority once detected in these settings. This family of viruses also comprises the genera novirhabdovirus, which exclusively infects fish. Rhabdovirus single stranded,linear,negative sense,non segmented. They consist of a lipid envelope with glycoprotein peplomers surrounding a helically wound nucleocapsid. We used deep sequencing, a method for generating millions of dna sequence reads from clinical samples, to discover a novel rhabdovirus bascongo virus, or basv associated with a 2009 outbreak of 3 human cases of acute hemorrhagic fever in mangala village, democratic republic of congo drc, africa. Rhabdovirus has become recognized as the generic term for those viruses which exhibit a bulletshaped or bacilliform morphology wildy, 1971. Under favourable conditions, the virus propagates along nerve tissue from the wound to the. Rabies virus structure and pathogenesis microbeonline.
The virus, a rhabdovirus, is often present in the salivary glands of rabid animals and is excreted in the saliva. Rhabdovirus family rhabdoviridae has a single negativestrand rna genome. The rhabdovirus ranscriptase proceeds in a 3 to 5 direction on the genome and the transcription terminates randomly at the end of protein sequences. It then spreads centrifugally to numerous other organs. Rabies virus is an enveloped, singlestranded rna virus with bullet shaped or rodshaped morphology.
The bullets surrounding the smooth gray circle are rabies. With the rural farm towns surrounding small cities like northampton all swinging 100% blue, where one would normally expect them to be red. Therefore, understanding the interactions of rhabdoviruses with insects is crucial to assessing rhabdovirus disease epidemiology. Rabies atau penyakitanjing gila merupakan penyakit mematikan yang disebabkan oleh virus rhabdovirus yang menyerang sistem saraf pusat ssp hewan mamalia termasuk manusia. If so, share your ppt presentation slides online with. Rhabdoviridae a family of arborviruses carried by arthropods arborvirus, arbovirus a large heterogeneous group of rna viruses divisible into. There is no practical way to prevent occupational exposure. The difficulty of assigning an official taxonomy is explained. It is a zoonotic virus and is transmissible to humans from the vesicular fluids and tissues of infected animals.
About 95% of human deaths occur in asia and africa. Food and drug administration, bethesda, maryland, usa. A simple alphabetical classification is offered as a means to codify the proteins of rhabdoviruses, using vesicular stomatitis virus as the prototype. Ppt rabies powerpoint presentation free to download. The evolutionary challenge faced by rna viruses is to maximize functional diversity within severe constraints on genome size.
A novel rhabdovirus associated with acute hemorrhagic fever in. Albert joubert 7 fish novirhabdoviruses 89 gael kurath 8 the sigma viruses of drosophila 117 ben longdon, lena wilfert and francis m. The adobe flash plugin is needed to view this content. Get a printable copy pdf file of the complete article 5. Rhabdovirus free download as powerpoint presentation. Rabies is a viral infection that mainly spreads through a bite from an infected animal. Identification of a novel rhabdovirus in spodoptera frugiperda cell. Early rabies it has been recognized in india since the vedic period 1500500 bc and is described in the ancient indian scripture atharvaveda, rabies is endemic in india, a vast country with a population exceeding 1. A novel rhabdovirus associated with acute hemorrhagic. Plant rhabdoviruses are transmitted by and replicate in hemipteran insects such as aphids aphididae, leafhoppers cicadellidae, or planthoppers delphacidae.
Identification of a novel rhabdovirus in spodoptera frugiperda cell lines. Rhabdoviridae synonyms, rhabdoviridae pronunciation, rhabdoviridae translation, english dictionary definition of rhabdoviridae. Susceptible to disinfectants inactivated by drying electron micrograph of rabies. In general, vhsv causes severe degeneration in the hematopoietic tissues of affected fish. Infections from trauma bites rabies rhabdovirus ssrna zoonosis. Rhabdovirus definition is any of a family rhabdoviridae of rod or bulletshaped singlestranded rna viruses found in plants and animals and including the causative agents of rabies and vesicular stomatitis. Pdf outbreak of hirame rhabdovirus infection in cultured. The family rhabdoviridae consists of more than 100 singlestranded, negative sense, nonsegmented viruses that infect a wide variety of hosts, including.
The rhabdovirus maraba has recently been characterized as a potent oncolytic virus. Rhabdoviruses contains a detailed table of more than 100 taxonomically unassigned viruses, of which more than 90% are unassigned animal rhabdoviruses mostly isolated from arthropods. For example, if a transcription finishes at the end of m sequence. Winner of the standing ovation award for best powerpoint templates from presentations magazine. Rabies virus, epidemiology, transmission and freeroaming cats. The two plant rhabdovirus genera, nucleorhabdovirus and cytorhabdovirus, can be distinguished on the basis of their intracellular site of morphogenesis in plant cells. Most human deaths follow a bite from an infected dog. Here, we focus on vesicular stomatitis virus vsv, a prototype of animal rhabdovirus. Ma h1, galvin ta1, glasner dr1, shaheduzzaman s1, khan as2. Jiggins 9 virushost protein interactions of plantadapted rhabdoviruses 3. The family rhabdoviridae consists of more than 100 singlestranded, negativesense, nonsegmented viruses that infect a wide variety of hosts, including. Most and perhaps all plant rhabdoviruses are rounded at both ends to give a bacilliform shape. Worlds best powerpoint templates crystalgraphics offers more powerpoint templates than anyone else in the world, with over 4 million to choose from.
Author summary understanding the patterns and mechanisms of genome evolution is one of the most important, yet least understood, aspects of rna virus biology. Virus tersusun dari ribonukleokapsid dibagian tengah, memiliki membrane selubung amplop dibagian luarnya yang pada permukaannya terdapat tonjoloan spikes yang jumlahnya lebih dari 500 buah. On the basis of rhabdovirus phylogeny and the broad host ranges of rhabdoviruses, we propose that insects are the primary determinants of the rhabdovirus plant and animal host range. We currently have several openings for writing workers.
Rabies is the most notable human disease that is caused by this family of viruses. However, while ive been looking for a group, ive noticed that most people are outside what i as an outsider consider cincinnati proper. Ppt rhabdoviridae powerpoint presentation free to download id. These specific interactions between plants, viruses and insects offer new insights into host adaptation and molecular virus evolution. Quizlet flashcards, activities and games help you improve your grades. Rabies is an infectious viral disease caused by rabies virus. Pdf maraba virus as a potent oncolytic vaccine vector. Single stranded,linear,negative sense,non segmented rna. Rabies ppt by dr sujith chadala slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. Between 30% to 60% of the victims of dog bites are children under the age of 15. In the case of the fish vesiculovirus spring viremia of carp virus svcv there is a single serotype. Evolution of genome size and complexity in the rhabdoviridae. We performed an extensive analysis of our sf9 cell bank atcc crl1711 lot 5814 sf9l5814 to determine whether this virus was already present in cells obtained from atcc in 1987. Virions 100430 by 45100 nm, formed by budding from surface membranes of cells, are enveloped and ether sensitive, with surface spikes 510 nm long.
Genomics and structurefunction studies of rhabdoviridae proteins. A free powerpoint ppt presentation displayed as a flash slide show on id. Antibodies directed against svcv crossreact to various degrees with other fish rhabdoviruses. If you continue browsing the site, you agree to the use of cookies on this website. Bs,microbiology 5 structure of the rabies virus 5 insert figure 25. The rhabdoviruses are approximately 70 nm wide and 170 nm long. Outbreak of hirame rhabdovirus infection in cultured spotted sea bass lateolabrax maculatus on the western coast of korea article pdf available in journal of fish diseases 3910 june 2016. Most contributions are written from a molecular and genomic perspective and contain expert insights upon which to base future research efforts. Rhabdovirus 0 points 1 point 2 points 3 years ago i think western mass is an interesting case.
Virus berukuran panjang 180 nm, diameter 75 nm, tonjolan berukuran 9 nm, dan jarak antara spikes 4. Pdf rabies is an incurable albeit preventable disease that remains an important human health issue. There is no evidence to suggest that an apparently healthy blood donor can transmit rabies, even if incubating clinical rabies. Enveloped, bulletshaped, 45100 nm in diameter, 100430 nm in length nucleic acid. Pada membran selubung amplop terdapat kandungan lemak yang tinggi. Rabies virus family rhabdoviridae jack lam atsuko hilliard roger salinas what is rabies. Arthropodborne rhabdoviruses of ruminants, with large, complex genomes 59 peter j. Rao md 1 slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. Pathogenesis enters the body through breaks in the mucosa.
Consists of wound care, rabies immune globulin, and vaccine. A putative novel rhabdovirus sfrv was previously identified in a spodoptera frugiperda cell line sf9 cells atcc crl1711 lot 58078522 by next generation sequencing and extensive bioinformatic analysis. Presentations ppt, key, pdf logging in or signing up. The family rhabdoviridae are negatively stranded rna viruses consisting of two genera that infect animals lyssavirus and vesiculovirus and the plant rhabdovirus group. Rhabdoviruses study guide by ccmusgrove includes 18 questions covering vocabulary, terms and more. Two of the genera within the family, vesiculovirus and lyssavirus, are more familiarly known as the causative agents of vesicular stomatitis and rabies in humans. The rhabdoviridae represent one of the oldest and most feared viral families to plague humankind. Schneider general rabies info rabies is a violently deadly animal disease spreads as a virus through animals such as. Rhabdovirus definition of rhabdovirus by merriamwebster. Rabies virus, which causes fatal encephalomyelitis, is the only significant human pathogen belonging to the rhabdovirus family. Sfrhabdovirus sequences were also found in the sf21 parental cell line of sf9 cells but not in other insect cell. Rhabdoviruses is the property of its rightful owner. Learn rhabdovirus with free interactive flashcards.